1.
Goodman DS, Smith FR, Seplowitz AH,
Ramakrishnan R, Dell RB. Prediction of the parameters of whole body cholesterol
metabolism in humans. Trans Assoc Am
Physicians. 92:257-67, 1979.
2.
Goodman DS, Smith FR, Seplowitz AH,
Ramakrishnan R, Dell RB. Prediction of the parameters of whole body cholesterol
metabolism in humans. J Lipid Res. 21:699-713, 1980.
3.
Kawakami M, Blum CB, Ramakrishnan R, Dell
RB, Goodman DS. Turnover of the plasma binding protein for vitamin D and its
metabolites in normal human subjects. J
Clin Endocrin Metab. 53:1110-6, 1981.
4.
Ramakrishnan R, Dell RB, Goodman DS. On
determining the extent of side-pool synthesis in a three-pool model for whole
body cholesterol kinetics. J Lipid Res.
22:1174-80, 1981.
5.
Goodman DS, Deckelbaum RJ, Palmer RH, Dell
RB, Ramakrishnan R, Delpre G, Beigel Y, Cooper M. Cholesterol turnover and
metabolism in two patients with abetalipoproteinemia. J Lipid Res. 24:1605-11, 1983.
6.
Ramakrishnan R, Leonard EF, Dell RB. A
proof of the occupancy principle and the mean transit time theorem for
compartmental models. Math Biosci.
68:121-136, 1984.
7.
Ramakrishnan R. An application of Berman's work on pool-model
invariants in analyzing indistinguishable models for whole-body cholesterol
metabolism. Math Biosci. 72:373-385,
1984.
8.
Varma DR, Ramakrishnan R. A rat model for
the study of transplacental pharmacokinetics and its assessment with antipyrine
and aminoisobutyric acid. J Pharmacol
Meth. 14:61-74, 1985.
9.
Dell RB, Mott GE, Jackson EM,
Ramakrishnan R, Carey KD, McGill HC Jr, Goodman DS. Whole body and tissue
cholesterol turnover in the baboon. J
Lipid Res. 26:327-37, 1985.
10. Dell
RB, Ramakrishnan R, Palmer RH, Goodman DS. A convenient six-point blood
sampling schedule for determining whole body cholesterol kinetics in humans. J Lipid Res. 26:575-82, 1985.
11. Blum
CB, Dell RB, Palmer RH, Ramakrishnan R, Seplowitz AH, Goodman DS. Relationship
of the parameters of body cholesterol metabolism with plasma levels of HDL
cholesterol and the major HDL apoproteins. J
Lipid Res. 26:1079-88, 1985.
12. Le
NA, Ramakrishnan R, Dell RB, Ginsberg HN, Brown WV. Kinetic analysis using
specific radioactivity data. Meth
Enzymol. 129:384-95, 1986.
13. Moessinger
AC, Mills JL, Harley EE, Ramakrishnan R, Berendes HW, Blanc WA. Umbilical cord
length in Down's syndrome. Am J Dis
Children. 140:1276-7, 1986.
14. Kashyap
S, Forsyth M, Zucker C, Ramakrishnan R, Dell RB, Heird WC. Effects of varying
protein and energy intakes on growth and metabolic response in low birth weight
infants. J Pediatr. 108:955-63, 1986.
15. Palmer
RH, Nichols AV, Dell RB, Ramakrishnan R, Lindgren FT, Gong EL, Blum CB, Goodman
DS. Lack of relationship in humans of the parameters of body cholesterol
metabolism with plasma levels of subfractions of HDL or LDL, or with apoE
isoform phenotype. J Lipid Res. 27:637-44,
1986.
16. Schulze
KF, Stefanski M, Masterson J, Kashyap S, Sanocka U, Forsyth M, Ramakrishnan R,
Dell R. An analysis of the variability in estimates of bioenergetic variables
in preterm infants. Pediatr Res.
20:422-7, 1986.
17. Ginsberg
HN, Le NA, Short MP, Ramakrishnan R, Desnick RJ. Suppression of apolipoprotein
B production during treatment of cholesteryl ester storage disease with
lovastatin. Implications for regulation of apolipoprotein B synthesis. J Clin Invest. 80:1692-7, 1987.
18. Kashyap
S, Schulze KF, Ramakrishnan R, Dell RB, Heird WC. Effects of protein and energy
intakes on growth [letter]. J Pediatr.
110:815, 1987.
19. Schulze
KF, Stefanski M, Masterson J, Spinnazola R, Ramakrishnan R, Dell RB, Heird WC.
Energy expenditure, energy balance, and composition of weight gain in low birth
weight infants fed diets of different protein and energy content. J Pediatr. 110:753-9, 1987.
20. Makover
A, Moriwaki H, Ramakrishnan R, Saraiva MJ, Blaner WS, Goodman DS. Plasma
transthyretin. Tissue sites of degradation and turnover in the rat. J Biol Chem. 263:8598-603, 1988.
21. Kashyap
S, Schulze KF, Forsyth M, Zucker C, Dell RB, Ramakrishnan R, Heird WC. Growth,
nutrient retention, and metabolic response in low birth weight infants fed
varying intakes of protein and energy. J
Pediatr. 113:713-21, 1988.
22. Whitlock
ME, Swenson TL, Ramakrishnan R, Leonard MT, Marcel YL, Milne RW, Tall AR.
Monoclonal antibody inhibition of cholesteryl ester transfer protein activity
in the rabbit. Effects on lipoprotein composition and HDL cholesteryl ester
metabolism. J Clin Invest. 84:129-37,
1989.
23. Arad
Y, Ramakrishnan R, Ginsberg HN. Lovastatin therapy reduces low density
lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing
the production of apoB-containing lipoproteins: implications for the
pathophysiology of apoB production. J
Lipid Res. 31:567-82, 1990.
24. Kashyap
S, Schulze KF, Forsyth M, Dell RB, Ramakrishnan R, Heird WC. Growth, nutrient
retention, and metabolic response of low-birth-weight infants fed supplemented
and unsupplemented preterm human milk. Am
J Clin Nutr. 52:254-62, 1990.
25. Goldberg
IJ, Blaner WS, Vanni TM, Moukides M, Ramakrishnan R. Role of lipoprotein lipase
in the regulation of high density lipoprotein
apolipoprotein metabolism. Studies in normal and lipoprotein lipase-inhibited
monkeys. J Clin Invest. 86:463-73,
1990.
26. Ramakrishnan
R, Arad Y, Wong S, Ginsberg HN. Nonuniform radiolabeling of VLDL apolipoprotein
B: implications for the analysis of studies of the kinetics of the metabolism
of lipoproteins containing apolipoprotein B. J Lipid Res. 31:1031-42, 1990.
27. Rosen
JM, Butler SP, Meinken GE, Wang TS, Ramakrishnan R, Srivastava SC, Alderson PO,
Ginsberg HN. Indium-111-labeled LDL: a potential agent for imaging
atherosclerotic disease and lipoprotein biodistribution. J Nuclear Med. 31:343-50, 1990.
28. Ginsberg
HN, Barr SL, Gilbert A, Karmally W, Deckelbaum R, Kaplan K, Ramakrishnan R,
Holleran S, Dell RB. Reduction of plasma cholesterol levels in normal men on an
American Heart Association Step 1 diet or a Step 1 diet with added
monounsaturated fat. New Eng J Med.
322:574-9, 1990.
29. Goldberg
IJ, Holleran S, Ramakrishnan R, Adams M, Palmer RH, Dell RB, Goodman DS. Lack
of effect of lovastatin therapy on the parameters of whole-body cholesterol
metabolism. J Clin Invest. 86:801-8,
1990.
30. Dell
RB, Hein K, Ramakrishnan R, Puig-Antich J, Cooper T. Model for the kinetics of
imipramine and its metabolites in adolescents. Therapeutic Drug Monitoring. 12:450-9, 1990.
31. Quinet
E, Tall A, Ramakrishnan R, Rudel L. Plasma lipid transfer protein as a
determinant of the atherogenicity of monkey plasma lipoproteins. J Clin Invest. 87:1559-66, 1991.
32. Varma
DR, Ramakrishnan R. Effects of protein-calorie malnutrition on transplacental
kinetics of aminoisobutyric acid in rats. Placenta. 12:277-84, 1991.
33. Barr
SL, Ramakrishnan R, Johnson C, Holleran S, Dell RB, Ginsberg HN. Reducing total
dietary fat without reducing saturated fatty acids does not significantly lower
total plasma cholesterol concentrations in normal males. Am J Clin Nutr. 55:675-81, 1992.
34. Arad
Y, Ramakrishnan R, Ginsberg HN. Effects of lovastatin therapy on VLDL
triglyceride metabolism in subjects with combined hyperlipidemia: evidence for
reduced assembly and secretion of triglyceride-rich lipoproteins. Metabolism. 41:487-93, 1992.
35. Aalto-Setala
K, Fisher EA, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan
R, Ginsberg HN, Breslow JL. Mechanism of hypertriglyceridemia in human
apolipoprotein (apo) CIII transgenic mice. Diminished very low density
lipoprotein fractional catabolic rate associated with increased apo CIII and
reduced apo E on the particles. J Clin
Invest. 90:1889-900, 1992.
36. Goldberg
IJ, Vanni TM, Ramakrishnan R. Effects of intralipid-induced
hypertriglyceridemia on plasma high-density lipoprotein metabolism in the
cynomolgus monkey. Metabolism.
41:1176-84, 1992.
37. Deckelbaum
RJ, Ramakrishnan R, Eisenberg S, Olivecrona T, Bengtsson-Olivecrona G.
Triacylglycerol and phospholipid hydrolysis in human plasma lipoproteins: role
of lipoprotein and hepatic lipase. Biochemistry.
31:8544-51, 1992.
38. Horowitz
BS, Goldberg IJ, Merab J, Vanni TM, Ramakrishnan R, Ginsberg HN. Increased
plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in
subjects with low levels of high density lipoprotein cholesterol. J Clin Invest. 91:1743-52, 1993.
39. Schulze
K, Kashyap S, Ramakrishnan R. Cardiorespiratory costs of growth in low birth
weight infants. J Dev Physiol. 19:85-90, 1993.
40. Ginsberg
HN, Ngai C, Wang XJ, Ramakrishnan R. Increased production rates of LDL are
common in individuals with low plasma levels of HDL cholesterol, independent of
plasma triglyceride concentrations. Arterioscler
Thromb. 13:842-51, 1993.
41. Aalto-Setala
K, Bisgaier CL, Ho A, Kieft KA, Traber MG, Kayden HJ, Ramakrishnan R, Walsh A,
Essenburg AD, Breslow JL. Intestinal expression of human apolipoprotein A-IV in
transgenic mice fails to influence dietary lipid absorption or feeding
behavior. J Clin Invest. 93:1776-86,
1994.
42. Shachter
NS, Hayek T, Leff T, Smith JD, Rosenberg DW, Walsh A, Ramakrishnan R, Goldberg
IJ, Ginsberg HN, Breslow JL. Overexpression of apolipoprotein CII causes
hypertriglyceridemia in transgenic mice. J
Clin Invest. 93:1683-90, 1994.
43. Ginsberg
HN, Karmally W, Siddiqui M, Holleran S, Tall AR, Rumsey SC, Deckelbaum RJ,
Blaner WS, Ramakrishnan R. A dose-response study of the effects of dietary
cholesterol on fasting and postprandial lipid and lipoprotein metabolism in
healthy young men. Arterioscler Thromb.
14:576-86, 1994.
44. Schmidt
AM, Mora R, Cao R, Yan SD, Brett J, Ramakrishnan R, Tsang TC, Simionescu M,
Stern D. The endothelial cell binding site for advanced glycation end products
consists of a complex: an integral membrane protein and a lactoferrin-like
polypeptide. J Biol Chem. 269:9882-8,
1994.
45. Ginsberg
HN, Karmally W, Barr SL, Johnson C, Holleran S,
Ramakrishnan R. Effects of increasing dietary polyunsaturated fatty
acids within the guidelines of the AHA step 1 diet on plasma lipid and
lipoprotein levels in normal males. Arterioscler
Thromb. 14:892-901, 1994.
46. Kashyap
S, Schulze KF, Ramakrishnan R, Dell RB, Heird WC. Evaluation of a mathematical
model for predicting the relationship between protein and energy intakes of
low-birth-weight infants and the rate and composition of weight gain. Ped Res. 35:704-12, 1994.
47. Traber
MG, Ramakrishnan R, Kayden HJ. Human plasma vitamin E kinetics demonstrate
rapid recycling of plasma RRR-alpha-tocopherol. Proc Nat Acad Sci. 91:10005-8, 1994.
48. Rumsey
SC, Stucchi AF, Nicolosi RJ, Ginsberg HN, Ramakrishnan R, Deckelbaum RJ. Human
plasma LDL cryopreserved with sucrose maintains in vivo kinetics
indistinguishable from freshly isolated human LDL in cynomolgus monkeys. J Lipid Res. 35:1592-8, 1994.
49. Weinstock PH, Bisgaier CL, Aalto-Setala K, Radner H, Ramakrishnan R, Levak-Frank S, Essenburg AD, Zechner R, Breslow JL. Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J Clin Invest. 96:2555-68, 1995.
50. Ginsberg HN, Karmally W, Siddiqui M, Holleran S, Tall AR, Blaner WS, Ramakrishnan R. Increases in dietary cholesterol are associated with modest increases in both LDL and HDL cholesterol in healthy young women. Arterioscler Thromb Vasc Biol. 15:169-78, 1995.
51. Kurlandsky SB, Gamble MV, Ramakrishnan R, Blaner WS. Plasma delivery of retinoic acid to tissues in the rat. J Biol Chem. 270:17850-7, 1995.
52. Shachter NS, Ebara T, Ramakrishnan R, Steiner G, Breslow JL, Ginsberg HN, Smith JD. Combined hyperlipidemia in transgenic mice overexpressing human apolipoprotein C-I. J Clin Invest. 98:846-55, 1996.
53. Resnick DJ, Gold RL, Lee-Wong M, Feldman BR, Ramakrishnan R, Davis WJ. Physicians' metered dose inhaler technique after a single teaching session. Annals of Allergy, Asthma, & Immunology. 76:145-8, 1996.
54. Towers HM, Schulze KF, Ramakrishnan R, Kashyap S. Energy expended by low birth weight infants in the deposition of protein and fat. Pediatr Res. 41:584-9, 1997.
55. Levak-Frank S, Weinstock PH, Hayek T, Verdery R, Hofmann W, Ramakrishnan R, Sattler W, Breslow JL, Zechner R. Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma. J Biol Chem. 272:17182-90, 1997.
56. Ebara T, Ramakrishnan R, Steiner G, Shachter NS. Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. J Clin Invest. 99:2672-81, 1997.
57. Lefevre M, Ginsberg HN, Kris-Etherton PM, Elmer PJ, Stewart PW, Ershow A, Pearson TA, Roheim PS, Ramakrishnan R, Derr J, Gordon DJ, Reed R. ApoE genotype does not predict lipid response to changes in dietary saturated fatty acids in a heterogeneous normolipidemic population. Arterioscler Thromb Vasc Biol. 17:2914-23, 1997.
58. Berglund L, Witztum JL, Galeano NF, Khouw AS, Ginsberg HN, Ramakrishnan R. Three-fold effect of lovastatin treatment on low density lipoprotein metabolism in subjects with hyperlipidemia: increase in receptor activity, decrease in apoB production, and decrease in particle affinity for the receptor. Results from a novel triple-tracer approach. J Lipid Res. 39:913-24, 1998.
59. Talmud PJ, Hall S, Holleran S, Ramakrishnan R, Ginsberg HN, Humphries SE. LPL promoter -93T/G transition influences fasting and postprandial plasma triglycerides response in African-Americans and Hispanics. J Lipid Res. 39:1189-96, 1998.
60. Ginsberg HN, Kris-Etherton P, Dennis B, Elmer PJ, Ershow A, Lefevre M, Pearson T, Roheim P, Ramakrishnan R, Reed R, Stewart K, Stewart P, Phillips K, Anderson N. Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA Study, protocol 1. Arterioscler Thromb Vasc Biol. 18:441-9, 1998.
61. Traber MG, Rader D, Acuff RV, Ramakrishnan R, Brewer HB, Kayden HJ. Vitamin E dose-response studies in humans with use of deuterated RRR-alpha-tocopherol. Am J Clin Nutr. 68:847-53, 1998.
62. Xu Y, Berglund L, Ramakrishnan R, Mayeux R, Ngai C, Holleran S, Tycko B, Leff T, Shachter NS. A common Hpa I RFLP of apolipoprotein CI increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E. J Lipid Res. 40:50-58, 1999.
63. Treskova E, Carpentier YA, Ramakrishnan R, Al-Haideri M, Seo T, Deckelbaum RJ. Blood clearance and tissue uptake of intravenous lipid emulsions containing long-chain and medium-chain triglycerides and fish oil in a mouse model. Jpen: Journal of Parenteral & Enteral Nutrition. 23:253-9, 1999.
64. Rinninger F, Wang N, Ramakrishnan R, Jiang XC, Tall AR. Probucol enhances selective uptake of HDL-associated cholesteryl esters in vitro by a scavenger receptor B-I-dependent mechanism. Arterioscler Thromb Vasc Biol. 19:1325-32, 1999.
65. Berglund L, Oliver EH, Fontanez N, Holleran S, Matthews K, Roheim PS, Ginsberg HN, Ramakrishnan R, Lefevre M. HDL-subpopulation patterns in response to reductions in dietary total and saturated fat intakes in healthy subjects. Am J Clin Nutr. 70:992-1000, 1999.
66. Ji Y, Wang N, Ramakrishnan R, Sehayek E, Huszar D, Breslow JL, Tall AR. Hepatic scavenger receptor BI promotes rapid clearance of high density lipoprotein free cholesterol and its transport into bile. J Biol Chem. 274:33398-402, 1999.
67. Kako Y, Huang LS, Yang J, Katopodis T, Ramakrishnan R, Goldberg IJ. Streptozotocin-induced diabetes in human apolipoprotein B transgenic mice. Effects on lipoproteins and atherosclerosis. J Lipid Res. 40:2185-94, 1999.
68. Goldberg IJ, Vanni-Reyes T, Ramakrishnan R, Holleran S, Ginsberg HN. Circulating lipoprotein profiles are modulated differently by lipoprotein lipase in obese humans. J Cardiovasc Risk. 7:41-7, 2000.
69. Ebara T, Conde K, Kako Y, Liu Y, Xu Y, Ramakrishnan R, Goldberg IJ, Shachter NS. Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice. J Clin Invest. 105:1807-18, 2000.
70. Gamble MV, Ramakrishnan R, Palafox NA, Briand K, Berglund L, Blaner WS. Retinol binding protein as a surrogate measure for serum retinol: studies in vitamin A-deficient children from the Republic of the Marshall Islands. Am J Clin Nutr. 73:594-601, 2001.
71. Traber MG, Winklhofer-Roob BM, Roob JM, Khoschsorur G, Aigner R, Cross C, Ramakrishnan R, Brigelius-Flohe R. Vitamin E kinetics in smokers and nonsmokers. Free Radic Biol Med. 31:1368-74, 2001.
72. Kashyap S, Ohira-Kist K, Abildskov K, Towers HM, Sahni R, Ramakrishnan R, Schulze K. Effects of quality of energy intake on growth and metabolic response of enterally fed low-birth-weight infants. Pediatr Res. 50:390-7, 2001.
73. Kashyap S, Sahni R, Ramakrishnan R. Following up randomized feeding studies - a way to test the fetal programming hypothesis. Pediatr Res. 50(2 Pt 2):13A, 2001.(Presented at the First World Congress on Fetal Origins of Adult Diseases, Bombay, Feb 2001)
74. Rubin J, Paultre F, Tuck CH, Holleran S, Reed RG, Pearson TA, Thomas CM, Ramakrishnan R, Berglund L. Apolipoprotein [a] genotype influences isoform dominance pattern differently in African Americans and Caucasians. J Lipid Res. 43:234-44, 2002.
75. Dell RB, Holleran S, Ramakrishnan R. Sample size determination. ILAR J. 43:207-13, 2002.
76. Magnano AR, Holleran S, Ramakrishnan R, Reiffel JA, Bloomfield DM. Autonomic nervous system influences on QT interval in normal subjects. J Am Coll Cardiol. 39:1820-6, 2002.
77. Ranjan N, Sarangi S, Padmanabhan VT, Holleran S, Ramakrishnan R, Varma DR. Methyl isocyanate exposure and growth patterns of adolescents in Bhopal. JAMA 290:1856-1857, 2003.
78. Quadro L, Hamberger L, Gottesman ME, Colantuoni V, Ramakrishnan R, Blaner WS. Transplacental Delivery of Retinoid: The Role of Retinol-Binding Protein and Lipoprotein Retinyl Ester. Am J Physiol Endocrinol Metab. 286(5):E844-51, 2004.
79. Magnano AR, Holleran S, Ramakrishnan R, Reiffel JA, Bloomfield DM. Autonomic modulation of the u wave during sympathomimetic stimulation and vagal inhibition in normal individuals. Pacing Clin Electrophysiol. 27:1484-92, 2004.
80. Conde-Knape K, Okada K, Ramakrishnan R, Shachter NS. Overexpression of apoC-III produces lesser hypertriglyceridemia in apoB-48-only gene-targeted mice than in apoB-100-only mice. J Lipid Res. 45:2235-44, 2004.
81. Berglund L, Ramakrishnan R. Lipoprotein(a): an elusive cardiovascular risk factor. Arterioscler Thromb Vasc Biol. 24:2219-26, 2004.
82. Leonard SW, Bruno RS, Ramakrishnan R, Bray T, Traber MG. Cigarette Smoking Increases Human Vitamin E Requirements as Estimated by Plasma Deuterium-Labeled CEHC. Ann N Y Acad Sci. 1031:357-60, 2004.
83. Brundert M, Ewert A, Heeren J, Behrendt B, Ramakrishnan R, Greten H, Merkel M, Rinninger F. Scavenger receptor class B type I mediates the selective uptake of high-density lipoprotein-associated cholesteryl ester by the liver in mice. Arterioscler Thromb Vasc Biol. 25:143-8, 2005.
84. Bruno RS, Ramakrishnan R, Montine TJ, Bray TM, Traber MG. {alpha}-Tocopherol disappearance is faster in cigarette smokers and is inversely related to their ascorbic acid status. Am J Clin Nutr. 81:95-103, 2005.
85. Bai D, Brar P, Holleran S, Ramakrishnan R, Green PH. Effect of gender on the manifestations of celiac disease: evidence for greater malabsorption in men. Scand J Gastroenterol. 40:183-7, 2005.
86. Leonard SW, Paterson E, Atkinson JK, Ramakrishnan R, Cross CE, Traber MG. Studies in humans using deuterium-labeled alpha- and gamma-tocopherols demonstrate faster plasma gamma-tocopherol disappearance and greater gamma-metabolite production. Free Radic Biol Med. 38:857-66, 2005.
87. Nagashima K, Lopez C, Donovan D, Ngai C, Fontanez N, Bensadoun A, Fruchart-Najib J, Holleran S, Cohn JS, Ramakrishnan R, Ginsberg HN. Effects of the PPARgamma agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus. J Clin Invest. 115:1323-1332, 2005.